From: Tamoxifen-associated vasculitis in a breast cancer patient
Reference | Age | Duration of tamoxifen intake | Other tamoxifen related toxicities/Comments |
---|---|---|---|
19 | 56 | 6 months | Mild increase of liver enzymes: AST (65; normal <40 U/L), and mildy decrease C4 (10; normal 15–45 mg%). Skin lesions reappeared when tamoxifen was newly indicated |
20 | 67 y | 4 weeks | None other toxicity was documented. Tamoxifen was withdrawn. |
This case | 53 y | 4 months | Increase of liver enzymes: alkaline phosphatase (196; normal: 40–150 U/L), GGT (213; normal> 12–43), ALT (249; normal 5–66 U/L), AST (110; normal 9–55 U/L). Very painful arthritis in knees, ankles |