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Table 1 Tamoxifen associated vasculitis. Case reports in the literature.

From: Tamoxifen-associated vasculitis in a breast cancer patient

Reference

Age

Duration of tamoxifen intake

Other tamoxifen related toxicities/Comments

19

56

6 months

Mild increase of liver enzymes: AST (65; normal <40 U/L), and mildy decrease C4 (10; normal 15–45 mg%).

Skin lesions reappeared when tamoxifen was newly indicated

20

67 y

4 weeks

None other toxicity was documented. Tamoxifen was withdrawn.

This case

53 y

4 months

Increase of liver enzymes: alkaline phosphatase (196; normal: 40–150 U/L), GGT (213; normal> 12–43), ALT (249; normal 5–66 U/L), AST (110; normal 9–55 U/L).

Very painful arthritis in knees, ankles