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Table 1 Clinical characteristics of patients with primary sphenoidal non-Hodgkin lymphoma previously described in the literature

From: Non-Hodgkin's lymphoma of the sphenoid sinus presenting as isolated oculomotor nerve palsy

Age (yrs)/sex

Clinical symptoms and signs

Local extension

Pathology

Treatment

Reference

52/M

Reduced visual acuity, diplopia, retroorbital pain Orbital apex syndrome with blindness

Left optic canal

Diffuse large B cell type

Radiotherapy Chemotherapy

Ueba et al [15]

39/M

Nasal congestion, facial pain, paresthesia

Sellar turcica

Diffuse large T cell type

Radiotherapy CHOP-M

Weber and Loewenheim [16]

44/M

Diplopia, bilateral abducens nerve palsy

Clivus, cavernous sinus, ethmoid sinus

Diffuse large B cell type

CHOP-M

Deleu et al [3]

78/M

Diplopia, abducens nerve palsy

Clivus, cavernous sinus

Diffuse large B cell type

Radiotherapy (45 Gy)

Ferrario et al [4]

5/M

Sudden visual loss, optic neuropathy

Suprasellar cavernous sinus

Diffuse large B cell type

Radiotherapy (60 Gy) Chemotherapy*

Roth and Siatkowski [12]

64/M

Headache, diplopia, oculomotor nerve palsy

Sellar turcica, cavernous sinus

Diffuse large B cell type

COPPA-M Radiotherapy (50 Gy)

Metellus et al [8]

53/F

Headache, ptosis, oculomotor nerve palsy

Cavernous sinus

Diffuse large B cell type

CHOP-R

Present case

  1. * CHOP-M = cyclophosphamide, adriamycin, vincristine, prednisone, and methotrexate; CHOP-R = cyclophosphamide, adriamycin, vincristine, prednisone, and rituximab; COPPA-M = cyclophosphamide, Oncovin, procarbazine, prednisone, adriamycin, and methotrexate.