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Table 2 Procedural and histopathology variables for the ultrasound-guided 8-gauge Mammotome® biopsy technique: For all cases (n = 304), for cases in which an attempt to completely excise the breast lesion was made (n = 235), and for cases in which only diagnostic tissue sampling of the breast lesion was undertaken (n = 69)

From: A comprehensive evaluation of the 8-gauge vacuum-assisted Mammotome® system for ultrasound-guided diagnostic biopsy and selective excision of breast lesions

 

All cases

(n = 304)

Attempted lesion excision

(n = 235)

Only diagnostic lesion sampling

(n = 69)

P-value

Estimated number of Mammotome® cores removed

8

(2–38)

9

(3–38)

6

(2–17)

< 0.001

Estimated volume of Mammotome® cores removed (cubic cm)

2.18

(0.26–37.13)

2.50

(0.60–37.13)

1.38

(0.26–4.38)

< 0.001

Percentage of estimated volume of Mammotome® cores removed as compared to volume of

original ultrasound lesion

615%

(9%–18,086%)

730%

(113%–18,086%)

222%

(9%–2263%)

< 0.001

Lesion histopathology

   

< 0.001

   Fibroadenoma

126

(41%)

112

(48%)

14

(20%)

 

   Other benign findings

107

(35%)

88

(37%)

19

(28%)

 

   Benign tumors

10

(3%)

7

(3%)

3

(4%)

 

   Invasive breast cancer

47

(16%)

20

(9%)

27

(39%)

 

   DCIS

4

(1%)

2

(1%)

2

(3%)

 

   ICPC

2

(1%)

1

(< 0.5%)

1

(1%)

 

   Lymphoma

3

(1%)

1

(< 0.5%)

2

(3%)

 

   SQBCC

1

(< 0.5%)

0

(0%)

1

(1%)

 

   Epithelial atypia

4

(1%)

4

(2%)

0

(0%)

 

Post-procedural complications (hematoma formation, skin ecchymosis, or both)

24

(8%)

20

(9%)

4

(6%)

0.462

  1. DCIS, ductal carcinoma in situ; ICPC, intracystic papillary carcinoma; SQBCC, subcutaneous basal cell carcinoma