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Table 1 Patient demographics, tumor characteristics, and intraoperative variables of invasive breast cancers (n = 353) in which a one SLN was identified versus two or more SLNs were identified.

From: Re-emphasizing the concept of adequacy of intraoperative assessment of the axillary sentinel lymph nodes for identifying nodal positivity during breast cancer surgery

 

One SLN identified (n = 104)

Two or more SLNs identified (n = 249)

P-value

Age (mean ± SD, years)

56 ± 11

56 ± 12

0.870

Height (mean ± SD, inches)

64 ± 3

64 ± 2

0.386

Weight (mean ± SD, pounds)

174 ± 45

165 ± 35

0.041

BMI (mean ± SD, kg/m2)

29.5 ± 6.9

28.3 ± 6.0

0.101

Breast size

  

0.053

   Small

6 (6%)

25 (10%)

 

   Medium

31 (30%)

101 (41%)

 

   Large

41 (39%)

83 (33%)

 

   Not available

26 (25%)

40 (16%)

 

Palpable tumor

53 (51%)

120 (48%)

0.635

Tumor location

  

0.259

   UOQ

51 (49%)

142 (57%)

 

   LOQ

21 (20%)

33(13%)

 

   UIQ

20 (19%)

38 (15%)

 

   LIQ

9 (9%)

21 (8%)

 

   Central

3 (3%)

15 (6%)

 

Type of diagnostic breast biopsy

  

0.301

   Core

79 (76%)

191 (77%)

 

   Excisional

24 (23%)

58 (23%)

 

   Fine needle aspiration

1 (1%)

0 (0%)

 

Pathologic T-stage

  

0.617

   T1

68 (65%)

176 (71%)

 

   T2

34 (33%)

69(28%)

 

   T3

2 (2%)

4 (2%)

 

Histopathology

  

0.958

   Ductal

90 (87%)

216 (87%)

 

   Lobular

3 (3%)

18 (7%)

 

   Mixed Ductal-Lobular

3 (3%)

9 (4%)

 

   Other

8 (8%)

6 (2%)

 

Histologic grade

  

0.032

   Well-differentiated

11 (11%)

56 (23%)

 

   Moderately-differentiated

47 (45%)

101 (41%)

 

   Poorly-differentiated

46 (44%)

92 (37%)

 

Estrogen receptor positive

77 (74%)

198 (80%)

0.258

Progesterone receptor positive

63 (61%)

165 (66%)

0.308

HER-2/neu positive

27 (26%)

46 (19%)

0.136

Lymphovascular invasion

24 (23%)

48 (19%)

0.419

Route of injection of 99 mTc-sulfur colloid

  

0.428

   Intradermal

33 (32%)

92 (37%)

 

   Intraparenchymal

38 (37%)

74 (30%)

 

   Subareolar

33 (32%)

83 (33%)

 

Surgery performed at time of SLN biopsy

  

0.184

   Lumpectomy

80 (77%)

169 (68%)

 

   Mastectomy

21 (20%)

74 (30%)

 

   SLN biopsy alone

3 (3%)

6 (2%)

 

Time from 99 mTc-sulfur colloid injection to SLN biopsy (mean ± SD, minutes)

290 ± 78

287 ± 66

0.682

  1. BMI, body mass index; UOQ, upper outer quadrant; LOQ, lower outer quadrant; UIQ, upper inner quadrant; LIQ, lower inner quadrant; SLN, sentinel lymph node.