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Table 4 Multivariate Cox regression analysis of factors possibly influencing cancer specific survival in patients with RCC.

From: Sporadic renal cell carcinoma in young and elderly patients: are there different clinicopathological features and disease specific survival rates?

  

stepwise reverse selection

  

adjusted HR

95% CI

P

Age

   

0.03

 

YP (≤45 years)

0.21

0.11 – 0.89

 
 

OP (≥75 years)

1.00

(reference)

 

pTNM stage

   

0.01

 

pT1+pT2

1.00

(reference)

 
 

pT3+pT4

2.82

0.74 – 10.49

 

Nodal status

   

0.04

 

N0

1.00

(reference)

 
 

N1, N2

2.37

0.95 – 5.69

 

M status

   

< 0.001

 

M0

1.00

(reference)

 
 

M1

20.61

3.32 – 127.78

 

Grade

   

< 0.001

 

G1+G2

1.00

(reference)

 
 

G3

1.65

0.18 – 15.08

 

Tumor diameter

   

< 0.01

 

< 7 cm

1.00

(reference)

 
 

≥7 cm

1.88

0.46 – 11.18

 

Histological subtype

    
 

Clear-cell

1.00

(reference)

 
 

Papillary

0.78

0.14 – 3.48

0.67

 

Chromophobe

1.02

0.21 – 5.75

0.90

 

Other histological types

0.68

0.06 – 6.56

0.71

Sex

    
 

Male

1.00

(reference)

 
 

Female

0.52

0.38 – 2.01

0.35

Clinical presentation

    
 

Asymptomatic

1.00

(reference)

 
 

Symptomatic

0.67

0.09 – 2.33

0.49

  1. bold face representing p-values < 0.05
  2. HR = hazard ratio
  3. CI = confidence interval
  4. RCC = renal cell carcinoma