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Table 3 Univariate Cox regression analysis of factors possibly influencing cancer specific survival in patients with RCC.

From: Sporadic renal cell carcinoma in young and elderly patients: are there different clinicopathological features and disease specific survival rates?

  

HR

95% CI

P

Age

   

0.02

 

YP (≤45 years)

0.37

0.15 – 0.72

 
 

OP (≥75 years)

1.00

(reference)

 

pTNM stage

   

0.002

 

pT1+pT2

1.00

(reference)

 
 

pT3 +pT4

3.46

1.72 – 12.49

 

Nodal status

   

< 0.001

 

N0

1.00

(reference)

 
 

N1, N2

5.57

1.98 – 15.64

 

M status

   

< 0.001

 

M0

1.00

(reference)

 
 

M1

35.99

9.88 – 131.02

 

Tumor grade

   

< 0.001

 

G1+G2

1.00

(reference)

 
 

G3

4.01

0.73 – 21.94

 

Tumor diameter

   

< 0.01

 

< 7 cm

1.00

(reference)

 
 

≥7 cm

1.76

0.40 – 10.38

 

Histological subtype

    
 

Clear-cell

1.00

(reference)

 
 

Papillary

1.43

0.46 – 4.97

0.54

 

Chromophobe

1.06

0.23 – 4.78

0.92

 

Other histological types

1.15

0.15 – 8.96

0.89

Sex

    
 

Male

1.00

(reference)

 
 

Female

0.61

0.24 – 1.56

0.29

Clinical presentation

   

0.002

 

Asymptomatic

1.00

(reference)

 
 

Symptomatic

4.41

1.71 – 11.37

 
  1. bold face representing p-values < 0.05
  2. HR = hazard ratio
  3. CI = confidence interval
  4. RCC = renal cell carcinoma