How useful is the assessment of lymphatic vascular density in oral carcinoma prognosis?

Table 2 Association of lymphatic and blood vessels invasion, as well as positive D2-40 immunoreaction in tumor cells, with the clinic-pathological data.

		Lymphatic invasion		Lymphatic invasion > 3		Blood vessel invasion			D2-40 positivity in tumor cells
	n	%	p	%	p	n	%	p	n	%	p
Age			0.056		0.886			0.157			0.474
> 50	15	66.7		40.0		13	0.0		15	80.0
≤ 50	16	93.8		37.5		14	14.3		16	68.8
Gender			0.474		0.066			0.773			0.419
Female	2	100.0		100.0		1	0.0		2	50.0
Male	29	79.3		34.5		26	7.7		29	75.9
Smoking history			0.257		0.245			0.678			0.419
Alcohol consumption			0.232		0.038			0.603			0.746
No	5	100.0		80.0		3	0.0		5	80.0
Yes	26	76.9		30.8		24	8.3		26	73.1
Mouth region			0.472		0.317			0.853			0.653
Differentiation			0.111		0.968			0.077			0.982
Well differentiated	7	57.1		42.9		6	0.0		7	71.4
Moderate differentiated	16	93.8		37.5		13	0.0		16	75.0
Poor differentiated	8	75.0		37.5		8	25.0		8	75.0
Desmoplasia			0.724		0.909			0.313			0.867
Perineural infiltration			0.283		0.035			0.693			0.319
Negative	20	75.0		25.0		17	5.9		20	80.0
Positive	11	90.9		63.6		10	10.0		11	63.6
T			0.763		0.625			0.299			0.935
N			0.791		0.756			0.189			0.253
Clinical Staging			0.998		0.640			0.467			0.294
Metastasis			0.232		0.286			0.540			0.746
Tumor recurrence			0.457		0.675			0.013			0.540
Negative	22	77.3		36.4		20	0.0		22	77.3
Positive	9	88.9		44.4		7	28.6		9	66.7
Outcome			0.290		0.039			0.259			0.867
Disease free	14	71.4		14.3		12	0.0		14	78.6
Dead for other reasons	3	66.7		66.7		3	0.0		3	66.7
Dead by the cancer consequences	14	92.9		57.1		12	16.7		14	71.4

Lymphatic invasion = any number of invaded lymphatic vessel. Lymphatic invasion > 3 = this number represents a median value.

ISSN: 1477-7819