Figure 4
From: Role of insulin-like growth factor binding protein-4 in prevention of colon cancer
(a) Electron microscopic image of tumours of BP-4 group at a magnification of × 710. Obviously there are numerous apoptotic cells with condensed nucleus (arrow) (b) Transmission electron microscopic imaging showing apoptotic cells which are seen as apoptotic bodies (arrow) with a shrunken nucleus and a condensed cytoplasm in BP-4 treated tumours (×11500)(c) Transmission electron microscopic imaging (×11500) showing apoptotic cells with dense masses of chromatin against nuclear membrane in BP-4 group tumours (d) Electron microscopy of control P group tumours showing necrotic cells (e) Transmission electron microscopic image of control M treated tumours (× 710) showing no apoptotic cells.