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Table 1 Characteristics of all sixteen breast lesions visualized on ultrasound examination.

From: The utilization of an ultrasound-guided 8-gauge vacuum-assisted breast biopsy system as an innovative approach to accomplishing complete eradication of multiple bilateral breast fibroadenomas

Lesion#

Breast

Ultrasound location† *

Palpable

Ultrasound lesion size (cm)

Ultrasound lesion volume (cm3)‡

1

Right

Central/Subareolar

Yes

9.63 × 8.28 × 4.94

206.24

2

Right

3 o'clock (zone 1)

Yes

1.53 × 1.51 × 1.17

1.41

3

Right

9 o'clock (zone 3)

No

1.25 × 0.76 × 0.40

0.2

4

Right

9 o'clock (zone 3)

No

0.73 × 0.72 × 0.64

0.18

5

Right

9 o'clock (zone 3)

No

0.62 × 0.46 × 0.32

0.05

6

Right

10 o'clock (zone 2)

No

0.66 × 0.64 × 0.41

0.09

7

Right

10 o'clock (zone 3)

No

1.43 × 1.34 × 0.80

0.8

8

Right

11 o'clock (zone 2)

No

1.24 × 0.81 × 0.46

0.24

9

Left

Central/Subareolar

Yes

2.87 × 2.46 × 1.27¶

4.69¶

10

Left

12 o'clock (zone 2)

No

0.96 × 0.77 × 0.36

0.14

11

Left

2 o'clock (zone 2)

No

0.96 × 0.84 × 0.53

0.22

12

Left

2 o'clock (zone 2)

No

0.91 × 0.84 × 0.39

0.16

13

Left

3 to 4 o'clock (zone 1)

Yes

1.39 × 1.32 × 0.77§

0.74§

14

Left

3 to 4 o'clock (zone 2)

Yes

3.30 × 2.85 × 1.48*

7.29*

15

Left

4 o'clock (zone 2)

No

0.87 × 0.79 × 0.36

0.13

16

Left

7 to 8 o'clock (zone 1)

No

0.55 × 0.53 × 0.25

0.04

  1. The location of each breast lesion seen on ultrasound was reported using its "o'clock" location and its 1, 2, or 3 "zone" location relative to the distance from the nipple (i.e., zone 1 is the central-third of the breast field, zone 2 is the middle-third of the breast field, and zone 3 is peripheral-third of the breast field) [20, 21].
  2. * All sixteen breast lesions visualized on ultrasound were also identified on MRI. However, the three closely approximated lesions (lesion #3, #4, and #5) that were ultimately identified on ultrasound in the 9 o'clock axis of zone 3 of the right breast could not be distinguished as three separate areas of enhancement on MRI, but appeared as one vaguely defined area of enhancement on MRI.
  3. The volume of the ultrasound lesion was calculated using the formula of the volume of an ellipsoid [4/3·π·length axis radius·width axis radius·height axis radius], rather than using the formula of the volume of a cuboid [length·width·height], since the three-dimensional shape of any given ultrasound lesion generally better approximated that of an ellipsoid rather than that of a cuboid [10].
  4. Seven months after stopping hormonal contraception, lesion #9 measured 2.35 × 1.63 × 0.79 cm in size (volume 1.58 cm3), consisting of a 166% volume reduction.
  5. § Four months after stopping hormonal contraception, lesion #13 measured 1.34 × 1.27 × 0.69 cm in size (volume 0.61 cm3), consisting of a 37% volume reduction.
  6. £Five and one-half months after stopping hormonal contraception, lesion #14 measured 2.12 × 1.91 × 0.98 cm in size (volume 2.08 cm3), consisting of a 186% volume reduction.