From: Relationship of hypoxia-inducible factor 1α and p21WAF1/CIP1 expression to cell apoptosis and clinical outcome in patients with gastric cancer
Factor
1-year survival
3-year survival
5-year survival
HIF-1αg(-), p21(+) n = 35
94.1
82.0
82.0***
HIF-1α (-), p21(-) n = 42
92.7
80.0
80.0**,***
HIF-1α (+), p21(+) n = 20
95.0
85.0
70.0*,**,***
HIF-1α (+), p21(-) n = 29
68.1
57.4
45.9*,**,***