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Table 4 Apoptosis associated with HIF-1α and p21 expression

From: Relationship of hypoxia-inducible factor 1α and p21WAF1/CIP1 expression to cell apoptosis and clinical outcome in patients with gastric cancer

Factor

Apoptotic index

HIF-1α (-), p21(+) n = 35

9.6 ± 7.33***

HIF-1α (-), p21(-) n = 42

9.83 ± 6.96**,***

HIF-1α (+), p21(+) n = 20

8.85 ± 4.04*,**,***

HIF-1α (+), p21(-) n = 29

6.97 ± 4.22*,**,***

  1. * P = 0.129 ** P = 0.037 *** P = 0.078 (mean ± S.D.)