Cyclin D1 and Rb protein expression and their correlation with prognosis in patients with colon cancer

Table 1 Cyclin D1 and pRb expression in relation to different clinico-pathological characteristics (X²)

Variable	No of cases	Cyclin D1 expression		P value	pRb expression		P value
		Negative	Positive		Negative	Positive
Age
<70	52	15	37	0,139	18	34	0.770
>70	59	25	34		22	37
Dukes' stage
A and B	60	22	38	0,881	22	38	0.881
C and D	51	18	33		18	33
Differentiation
Well + Moderate	91	36	55	0,099	30	61	0.151
Poor	20	4	16		10	10
Tumor location
Proximal	38	12	26	0,480	17	21	0.168
Distal	73	28	45		23	50
Lymph node metastas
Negative	68	22	45	0,541	23	45	0.541
Positive	43	17	26		17	26
Liver metastasis
Negative	93	36	57	0,182	34	59	0.794
Positive	18	4	14		6	12
Venous invasion
Negative	83	31	52	0,620	28	55	0.385
Positive	28	9	19		12	16

ISSN: 1477-7819