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Table 1 Proposed approach for defining risk of aggressive behavior in GIST, by Fletcher [2]

From: Surgical resection for gastrointestinal stromal tumors (GIST): experience on 25 patients

  Tumor Size (cm) Mitotic count
Very low risk < 2 cm < 5/50 HPF
Low risk 2–5 cm < 5/50 HPF
Intermediate risk < 5 cm 6–10/50 HPF
  5–10 cm < 5/50 HPF
High risk > 5 cm > 5/50 HPF
  > 10 cm any mitotic rate
  any size > 10/50 HPF