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Table 4 Response to NACT observed in various studies (22,27–31)

From: Role of p-glycoprotein expression in predicting response to neoadjuvant chemotherapy in breast cancer-a prospective clinical study

  Year Institute Neoadjuvant chemotherapy used Number of patients Response %
De Lena et al.[29] 1979 Southeastern cancer study group FAC 14 80
Morrow et al.[23] 1980 Guy's hospital AV 12 83
Aisner et al.[27] 1982 University of Maryland FAC 27 74
Sataloff et al.[30] 1994 Thomas Jefferson University Hospital CMF 189 85
Swain et al.[28] 1995 M.D. Anderson cancer center FAC 174 88
Singh et al.[22] 1996 PGI, Chandigarh India CMF 38 75.7
Present Study 2003–2004 VMMC, Safdarjang Hospital New Delhi FAC 50 60
  1. AV: [Adriamycin, Vincristine]
  2. CMF: [Cyclophosphamide. Methotrexate, 5-fluouracil]
  3. FAC [5-fluouracil, Adriamycin, Cyclophosphamide]