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Table 4 Response to NACT observed in various studies (22,27–31)

From: Role of p-glycoprotein expression in predicting response to neoadjuvant chemotherapy in breast cancer-a prospective clinical study

 

Year

Institute

Neoadjuvant chemotherapy used

Number of patients

Response %

De Lena et al.[29]

1979

Southeastern cancer study group

FAC

14

80

Morrow et al.[23]

1980

Guy's hospital

AV

12

83

Aisner et al.[27]

1982

University of Maryland

FAC

27

74

Sataloff et al.[30]

1994

Thomas Jefferson University Hospital

CMF

189

85

Swain et al.[28]

1995

M.D. Anderson cancer center

FAC

174

88

Singh et al.[22]

1996

PGI, Chandigarh India

CMF

38

75.7

Present Study

2003–2004

VMMC, Safdarjang Hospital New Delhi

FAC

50

60

  1. AV: [Adriamycin, Vincristine]
  2. CMF: [Cyclophosphamide. Methotrexate, 5-fluouracil]
  3. FAC [5-fluouracil, Adriamycin, Cyclophosphamide]