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Table 1 Randomised trial of intensive schedule versus standard schedule of follow-up of patients in the "GIVIO" trial

From: Guidelines, guidelines and more guidelines: And we still do not know how to follow-up patients with breast cancer

Intensive follow-up (n = 655)

Standard follow-up (n = 665)

• Physical examination every 3 months for 2 years; then 6monthly for 3 years

• Physical examination every 3 months for 2 years; then 6monthly for 3 years

• Serum biochemistry at each clinical examination

• Mammography annually

• Chest x-ray every 6 months

 

• Isotope bone scan annually

 

• Liver ultrasound annually

 

• Mammography annually

 
  1. (study detailed in JAMA 1994; 271: 1587–1592)