Transhiatal and transthoracic resection in adenocarcinoma of the esophagus: Does the operative approach have an influence on the long-term prognosis?

Table 1 Clinicopathological features

Clinicopathological features
	total			transhiatal (TH)			transthoracic (TT)			p-value
	(n = 150)			(n = 103)			(n = 47)
age (years)
median (range)	61 (28–78)			63 (28–78)			60 (35–75)			0.199
U-test
ASA classification
ASA II	62	145	42.8%	44	99	44.4%	18	46	39.1%	0.592
ASA III-IV	83	145	57.2%	55	99	55.6%	28	46	60.9%
Fisher's exact test
R classification
RO	131	149	87.9%	94	102	92.2%	37	47	78.7%	0.029
R1, R2	18	149	12.1%	8	102	7.8%	10	47	21.3%
Fisher's exact test
tumor localization
upper third	1	149	0.7%	0	103	0.0%	1	46	2.2%
middle third	15	149	10.1%	8	103	7.8%	7	46	15.2%	0.155
lower third	133	149	89.3%	95	103	92.2%	38	46	82.6%
Chi-Square (Pearson)
pT category
pT1	28	150	18.7%	27	103	26.2%	1	47	2.1%
pT2	39	150	26.0%	34	103	33.0%	5	47	10.6%	<0.0005
pT3	77	150	51.3%	41	103	39.8%	36	47	76.6%
pT4	6	150	4.0%	1	103	0.9%	5	47	10.6%
Chi-Square (Pearson)
pN category
pN0	51	146	34.9%	41	100	41.0%	10	46	21.7%	0.027
pN1-2	95	146	65.1%	59	100	59.0%	36	46	78.3%
Fisher's exact test
pM category
pM0	105	149	70.5%	75	102	73.5%	30	47	63.8%	0.250
pM1	44	149	29.5%	27	102	26.5%	17	47	36.2%
Fisher's exact test
UICC stage
UICC I-II	62	149	41.6%	53	102	52.0%	9	47	19.2%	<0.0005
UICC III-IV	87	149	58.4%	49	102	48.0%	38	47	80.9%
Chi-Square (Pearson)
tumor grading
G1	10	146	6.9%	8	100	8.0%	2	46	4.4%	0.167
G2	43	146	29.5%	32	100	32.0%	11	46	23.9%
G3	76	146	52.1%	46	100	46.0%	30	46	65.2%
G4	17	146	11.6%	14	100	14.0%	3	46	6.5%
Chi-Square (Pearson)
tumor length (grouped)
0–4 cm	69	143	48.3%	52	98	53.1%	17	45	37.8%	0.225
>4–8 cm	62	143	43.4%	39	98	39.8%	23	45	51.1%
>8 cm	12	143	8.4%	7	98	7.1%	5	45	11.1%
Chi-Square (Pearson)

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