Table 3 Lack of association between expression of E-Cadherin or β-Catenin and lymphovascular invasion, frequency of lymph node involvement or histologic grade
Preserved¶ | Impaired | |||||
|---|---|---|---|---|---|---|
Reduced Staining ▼ | Exclusively Cytoplasmic Staining | Negative Staining | Nuclear Staining | p value (impaired versus preserved expression) | ||
1) Lymphovascular invasion | ||||||
β-Catenin expression | ||||||
Absent (n = 83) | 20 | 7 | 2 | 54 | 0 | 0.4 |
Present (n = 60) | 20 | 12 | 3 | 25 | 0 | |
E-Cadherin expression | ||||||
Absent (n = 83) | 6 | 11 | 3 | 63 | 0 | 0.4 |
Present (n = 60) | 7 | 13 | 5 | 35 | 0 | |
2) Histological grade* | ||||||
β-Catenin expression | ||||||
1 (n = 31) | 8 | 3 | 1 | 19 | 0 | >0.05 for all comparisons |
2 (n = 53) | 20 | 7 | 1 | 25 | 0 | |
3 (n = 59) | 12 | 9 | 3 | 35 | 0 | |
E-Cadherin expression | ||||||
1 (n = 31) | 1 | 5 | 2 | 23 | 0 | >0.05 for all comparisons |
2 (n = 53) | 4 | 13 | 3 | 33 | 0 | |
3 (n = 59) | 8 | 6 | 3 | 42 | 0 | |
3) Lymph node Involvement | ||||||
β-Catenin expression | ||||||
Absent (n = 125) | 33 | 15 | 5 | 72 | 0 | 0.3 |
Present (n = 18) | 7 | 4 | 0 | 7 | 0 | |
E-Cadherin expression | ||||||
Absent (n = 125) | 9 | 21 | 7 | 88 | 0 | 0.06 |
Present (n = 18) | 4 | 3 | 1 | 10 | 0 | |