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Table 1 Data on 17 males with Secretory Breast Cancer

From: Secretory carcinoma of the breast containing the ETV6-NTRK3 fusion gene in a male: case report and review of the literature

Author Year Age Duration of symptoms Size (cm) Axillary status Treatment Hormone Receptors ETV6-NTRK3 Follow-up
Simpson31 1969 5 ND ND - (clinical) LE NE NE NED 4y
Tavassolli7 1980 9 ND ND - (clinical) LE NE NE NED 1.75y
Kari5 1985 3 1 mo 1.5 + (1/4) SM+ALNS NE NE ND
Roth32 1988 23 21y 2.0 - (0/21) MRM NE NE NED 4y
Krausz10 1989 24 Many years 4.0 ND SM + RT (axilla) NE NE DOD 20y
Serour21 1992 17 4 y 1.5 - (0/3) WLE + ALND ER- PR+ NE NED 5y
Lamovec18 1994 20 ND 1.2 - (0/?) MRM ER+ PR+ NE NED 1y
Pohar-Marinsek33 1994 20 6–7 y 1.2 - (clinical) SM ER+ PR+ NE NED 6 m
Kuwabara34 1988 66 3 y 3.0 + (2/?) MRM ER- PR+ NE NED 8 m
Vesoulis35 1998 33 10 y 1.5 ND MRM ER+ PR+ NE ND
Kameyama36 1998 50 ND 3.0 - (0/?) MRM ER+ NE ND
Chevallier37 1999 9 14 m 2.0 - (0/?) LE + ALND ER- PR- NE NED 45 m
Yildirim38 1999 11 1 y 1.5 + (1/18) MRT + CT+ RT ER - NE NED 12 m
Bhagwandeen39 1999–2000 9 1 m 1.2 - (0/15) MRM ER- PR- NE NED 20 m
De Bree22 2001 17 2 y 2.0 - (0–14) MRM ER- PR- NE NED 9 m
Grabellus40 2005 46 Male-female transexual ND 4.0 ND LE ER- PR- PRESENT ND
This case 2005 52 10 y 7 + 2/24 MRM + CT ER- PR- PRESENT AWD 25 m
  1. ND: no defined, LE: Local excision, MRM: Modified Radical Mastectomy, CT: chemotherapy, RT Radiotherapy, NE: not examined, NED: not evidence of disease, AWD: Alive with disease, ER: estrogen receptor, PR progesterone receptor. SM simple mastectomy, ALNS: axillary lymph node sampling, ALND: axillary lymph node dissection, WLE: wide local excision, DOD: Died of disease.