Figure 1From: Immunohistochemical detection of high-mobility group box 1 correlates with resistance of preoperative chemoradiotherapy for lower rectal cancer: a retrospective study HMGB1 Immunohistochemical staining of lower rectal carcinoma treated with chemoradiotherapy. (a) High HMGB1 expression (original magnification, ×200). HMGB1 is predominant in the nuclei of tumor cells, and shows diffuse and strong expression. (b) Tumors with low HMGB1 expression (original magnification, ×200). HMGB1 expression is observed in focal tumor cells.Back to article page