Table 1 Clinicopathological features among the three groups
Group 1 (n = 672) | Group 2 (n = 285) | Group 3 (n = 98) | P value | |
|---|---|---|---|---|
Age (year) * | 51.3 ± 8.9 | 69.3 ± 2.9 | 77.6 ± 2.6 | <0.001 |
Gender (%) | 0.203 | |||
Male | 398 (59.2) | 186 (65.3) | 58 (59.2) | |
Female | 274 (40.8) | 99 (34.7) | 40 (40.8) | |
BMI (kg/m 2 ) * | 23.5 ± 2.8 | 23.2 ± 3.0 | 23.0 ± 3.2 | 0.253 |
Comorbidity (number,%) | 171 (25.4) | 141 (49.5) | 66 (67.3) | <0.001 |
Hypertension** | 105 | 43 | 24 | |
Diabetes** | 46 | 25 | 6 | |
Heart disease** | 20 | 10 | 3 | |
Pulmonary disease** | 10 | 12 | 2 | |
Liver disease** | 28 | 6 | 3 | |
Kidney disease** | 2 | 1 | 0 | |
Others | 11 | 8 | 4 | |
Size of main lesion (mm) * | 2.8 ± 1.9 | 2.6 ± 1.6 | 3.0 ± 2.2 | 0.088 |
Histologic type | <0.001 | |||
Well differentiated | 129 | 98 | 26 | |
Moderately differentiated | 192 | 103 | 37 | |
Poorly differentiated | 253 | 71 | 26 | |
Signet ring cell | 82 | 5 | 2 | |
Other | 16 | 8 | 7 | |
Tumor location | 0.283 | |||
Upper | 39 | 17 | 5 | |
Middle | 211 | 79 | 21 | |
Lower | 422 | 189 | 72 | |
T stage *** (%) | 0.032 | |||
EGC | 538 (80.1) | 232 (81.4) | 68 (69.4) | |
AGC | 134 (19.9) | 53 (18.6) | 30 (30.6) | |
N stage *** | 0.260 | |||
N0 | 573 | 249 | 79 | |
N1–N3 | 99 | 36 | 19 | |
Stage *** | 0.084 | |||
IA | 534 | 228 | 67 | |
IB | 41 | 22 | 11 | |
IIA | 32 | 18 | 9 | |
IIB | 25 | 11 | 5 | |
IIIA | 14 | 4 | 4 | |
IIIB | 20 | 2 | 2 | |
IIIC | 6 | 0 | 0 |