Figure 3
From: Gene silencing of heparanase results in suppression of invasion and migration of hepatoma cells
Effect of TGS and PTGS of heparanase on migration of SMCC-7721 cells. At 48 h, 72 h and 96 h after TGS or PTGS transfection, SMCC-7721 cells were seeded in 35 mm plates and scratched. Pictures of the TGS group (A), PTGS group (B) and the control group (C) were taken 0 h and 24 h after the scratch and the average width of the gaps was then measured (D). *P < 0.05 and **P < 0.01 compared with 0 h. control: untransfected cells; p.s., post scratch; PTGS, post-transcriptional gene silencing; PTGS48h: 48 h after PTGS transfection; PTGS72h: 72 h after PTGS transfection; PTGS96h: 96 h after TGS transfection; TGS, transcriptional gene silencing; TGS48h: 48 h after TGS transfection; TGS72h: 72 h after TGS transfection; TGS96h: 96 h after TGS transfection. (D) Quantitation of the average width of the gaps.