Table 2 Clinicopathological characteristics of 73 second primary cancer (SPC) patients by other cancer first (OCF) and colorectal cancer first (CRCF)

Gender

Male/Female

23 (45.1)/28 (54.9)

11 (50.0)/11 (50.0)

0.700

Age (years)

<65/≥65

21 (41.2)/30 (58.8)

10 (45.5)/12 (54.5)

0.734

Interval diagnosis time (years)

8.7 ± 8.32

2.9 ± 1.98

0.002

HBV and HCV carrier

Yes/No

7 (13.7)/44 (86.3)

6 (27.3)/16 (72.7)

0.165

BMI (kg/m²)

<22/≥22

24 (47)/27 (53)

10 (45.5)/12 (54.5)

0.916

Albumin (gm/dL)

<3.5/≥3.5

24 (47)/27 (53)

8 (36.3)/14 (63.7)

0.390

Tumor size (cm)

≥5/<5

23 (45.1)/28 (54.9)

6 (27.3)/16 (72.7)

0.136

Tumor location^a

0.158

Right colon

15 (29.4)

3 (13.6)

Left colon

25 (49.0)

10 (45.5)

Rectum

11 (21.6)

9 (40.9)

TNM stage

III + IV/I + II

26 (51)/25 (49)

9 (40.9)/13 (59.1)

0.429

Vascular invasion

Yes/No

16 (31.4)/35 (68.6)

8 (36.4)/14 (63.6)

0.632

Perineurial invasion

Yes/No

18 (35.3)/33 (64.7)

4 (18.2)/18 (81.8)

0.159

Histology type

PD/WD + MD

6 (11.8)/45 (88.2)

2 (9.1)/20 (90.9)

0.864

Depth

T3 + T4/T1 + T2

43 (84.3)/8 (15.7)

17 (77.3)/5 (22.7)

0.635

Lymph Node

N1 + N2/N0

23 (43.1)/28 (54.9)

8 (36.4)/14 (63.6)

0.488

Pre-operation CEA (ng/mL)

≥5/<5

25 (49)/26 (51)

14 (63.6)/8 (36.4)

0.226

Chemotherapy

Yes/No

27 (52.9)/24 (47.1)

15 (68.2)/7 (31.8)

0.206

Diabetes mellitus

Yes/No

11 (21.6)/40 (78.4)

4 (18.2)/18 (81.8)

0.742

Cardiac disease

Yes/No

5 (9.8)/46 (90.2)

4 (18.2)/18 (81.8)

0.318