Table 2 Univariate and multivariate analyses in 483 patients with ESCC
Survival (%) | Univariate analysis HR (95% CI) | P-value | Multivariate analysis HR (95% CI) | P-value | |
|---|---|---|---|---|---|
Age (years) | 0.780 | 0.508 | |||
≤60 | 49.5 | 1.000 | 1.000 | ||
>60 | 49.5 | 1.075 (0.647-1.785) | 1.092 (0.841-1.420) | ||
Gender | 0.071 | 0.384 | |||
Female | 61.1 | 1.000 | 1.000 | ||
Male | 47.4 | 1.437 (0.969-2.131) | 1.197 (0.798-1.795) | ||
Tumor location | 0.069 | 0.189 | |||
Upper/Middle | 53.6 | 1.000 | 1.000 | ||
Lower | 44.0 | 1.262 (0.982-1.623) | 1.187 (0.915-1.539) | ||
Tumor length (cm) | <0.001 | 0.561 | |||
≤3 | 66.7 | 1.000 | 1.000 | ||
>3 | 42.6 | 2.158 (1.564-2.977) | 1.116 (0.771-1.616) | ||
Vessel involvement | 0.001 | 0.607 | |||
Negative | 52.6 | 1.000 | 1.000 | ||
Positive | 32.9 | 1.673 (1.228-2.279) | |||
1.088 (0.788-1.502) | |||||
Perineural invasion | 0.028 | 0.331 | |||
Negative | 51.8 | 1.000 | 1.000 | ||
Positive | 39.8 | 1.397 (1.036-1.884) | 1.168 (0.854-1.598) | ||
Differentiation | 0.008 | 0.015 | |||
Well/Moderate | 51.9 | 1.000 | 1.000 | ||
Poor | 38.6 | 1.507 (1.114-2.040) | 1.481 (1.081-2.030) | ||
Depth of invasion | <0.001 | 0.024 | |||
T1-2 | 68.0 | 1.000 | 1.000 | ||
T3-4 | 39.5 | 2.363 (1.746-3.199) | 1.521 (1.056-2.191) | ||
Nodal metastasis | <0.001 | <0.001 | |||
Negative | 65.0 | 1.000 | 1.000 | ||
Positive | 29.2 | 2.795 (2.158-3.621) | 2.105 (1.586-2.795) | ||
NLR | <0.001 | 0.039 | |||
<3.5 | 57.7 | 1.000 | 1.000 | ||
≥3.5 | 35.4 | 1.947 (1.513-2.506) | 1.339 (1.015-1.768) | ||
PLR | <0.001 | <0.001 | |||
<150 | 63.5 | 1.000 | 1.000 | ||
≥150 | 32.7 | 2.245 (1.735-2.904) | 1.840 (1.407-2.407) |