From: Choice of therapeutic strategies in intrathoracic anastomotic leak following esophagectomy
Group | P-value | ||
---|---|---|---|
Contained leak | Uncontained leak | ||
Number of patients (n) | 15 | 18 | |
Age (years) | 56.2 ± 11.0 | 64.8 ± 6.6 | 0.01* (t-test) |
Gender (n) | 0.18 | ||
Male | 10 | 14 | |
Female | 5 | 4 | |
Tumor location (n) | 0.6 | ||
Upper third | 0 | 1 | |
Middle third | 9 | 9 | |
Lower third/GEJ | 6 | 8 | |
Tumor type (n) | 0.01* (χ2 test) | ||
SCC | 12 | 15 | |
ADC | 3 | 2 | |
Neoadjuvant therapy (n) | 0.64 | ||
None | 14 | 16 | |
CT | 1 | 1 | |
RT | 0 | 1 | |
TNM stage (n) | 0.23 | ||
I | 4 | 1 | |
II | 6 | 7 | |
III | 5 | 9 | |
Subgroup (n) | 0.77 | ||
Early leak | 5 | 11 | |
Late leak | 10 | 7 | |
Interval of diagnosis of leak (days) | 12.6 ± 8.9 | 6.9 ± 3.9 | 0.019* (t-test) |
Treatment of leak (n) | |||
Conservative | 11 | 9 | |
Surgical exploration | 4 | 9 | |
Outcome of treatment (n) | 0.118 | ||
Cured patients | 14 | 12 | |
Hospital mortality | 1 | 6 (1 died of heart failure) |