Author | Cases | Age, years | Clinical presentation | Size, cm | Initial treatment | Outcome/follow up |
---|---|---|---|---|---|---|
Edelweiss and Malpica [1] | 1 | 36 | Right labium major mass | 5 | Excisional biopsy | LR at 12 months. AWD at 16 months |
Edelweiss and Malpica [1] | 2 | 57 | Right labium major mass | 3 | Excisional biopsy | LR at 60 months, then WLE (2x) until negative margin. NED at 216 months. |
Edelweiss and Malpica [1] | 3 | 69 | Mons pubis mass | 3 | Excisional biopsy + WLE | Dead of other causes at 144 months |
Edelweiss and Malpica [1] | 4 | 48 | Left paraclitoral mass | 1.2 | Excisional biopsy + WLE | LR, then WLE. NED at 144 months. |
Edelweiss and Malpica [1] | 5 | 46 | Right labium major pigmented lesion | 4 | Excisional biopsy + WLE (x2) | NED at 84 months. |
Edelweiss and Malpica [1] | 6 | 76 | Right labium major and crural fold mass | 15 | Excisional biopsy + WLE | LR at 7 months, then WLE with negative margin. At 14 months, metastasis to chest wall. At 18 months, metastasis to hip and thigh. Death of the disease at 34 months. |
Edelweiss and Malpica [1] | 7 | 44 | Left labium major mass | 4 | Excisional biopsy + WLE | NED at 53 months |
Edelweiss and Malpica [1] | 8 | 39 | Right labium major mass | N/A | WLE | LR at 48 months. Then, WLE with positive margin. At 60 months, local recurrence. Then WLE with positive margin. Used Gleevec. NED at 72 months |
Edelweiss and Malpica [1] | 9 | 30 | Right labium major and mons pubis mass | N/A | Excisional biopsy + WLE | LR at 11 months. Then, WLE. AWD at 24 months |
Edelweiss and Malpica [1] | 10 | 23 | Right labium major mass | 4 | Excisional biopsy + WLE | NED at 2 months |
Edelweiss and Malpica [1] | 11 | 30 | Left labium major mass | N/A | Excisional biopsy | LR at 60 months followed by WLE with positive margin. Then, partial vulvectomy with negative margin. NED at 96 months |
Edelweiss and Malpica [1] | 12 | 44 | Right labium major mass | 2.5 | Excisional biopsy + radical vulvectomy | NED at 36 months |
Edelweiss and Malpica [1] | 13 | 58 | Paraclitoral mass extending into vagina | 4.8 | WLE | NED at 3 months |
Soltan [10] | 14 | 83 | Left labium major/minor nodule | 5 | Excisional biopsy | N/A |
Agress et al. [11] | 15 | 56 | Left labium major | N/A | Excisional biopsy | LR, then WLE |
Bock et al. [12] | 16 | 52 | Right mons pruritus | 8 | Excisional biopsy | LR, then WLE |
Barnhill et al. [13] | 17 | 42 | Right vulva lateral to clitoris nodule | 1 | Excisional biopsy | LR, then WLE and hemivulvectomy |
Leake et al. [14] | 18 | 37 | Left mons and labium major nodule | 6.2 | Excisional biopsy | LR, then wide radical excision |
Leake et al. [14] | 19 | 59 | Right labium major nodule | 5 | Excisional biopsy | LR, then partial radical vulvectomy |
Panidis et al. [15] | 20 | 30 | Right labium major nodule | 2 | WLE | LR, then radical vulvectomy |
Aartsen and Albus-Lutter [16] | 21 | 50 | N/A | 1.2 | Radical vulvectomy | N/A |
Karlen et al. [17] | 22 | 36 | Left labium major irritated lump | 5 | WLE | N/A |
Nirenberg et al. [18] | 23 | 41 | Left labium major lump | 8 | WLE | N/A |
Alverez-Canas [19] | 24 | 58 | Left labium major mass | 3.2 | WLE | N/A |
Soergel et al. [20] | 25 | 47 | Left vulva mass + lung metastasis | 3 | Partial radical vulvectomy + chemotherapy | LR, then WLE + radiotherapy |
Ghorbani et al. [21] | 26 | 47 | Left paraclitoral area | N/A | Hemivulvectomy | LR, then wide radical excision |
Ghorbani et al. [21] | 27 | 44 | Left labium major mass | 4 | Wide radical excision | N/A |
Ghorbani et al. [21] | 28 | 66 | Mons mass | 1.5 | WLE | N/A |
Ghorbani et al. [21] | 29 | 36 | Right labium mass | 5 | Excsional biopsy | N/A |
Moodley and Moodley [22] | 30 | 39 | Left labium major mass | 12 | WLE | N/A |
Vanni et al. [23] | 31 | 39 | Inferior vulva/perineum mass | 6 | WLE | N/A |
Kholova et al. [24] | 32 | 31 | Left labium major recurrent nodule | 1.5 | Excisional biopsy | LR, then WLE + radiotherapy |
Ohlinger et al. [25] | 33 | 36 | Left vulva nodule | 2.8 | Excisional biopsy | LR, then WLE |
Hancox et al. [26] | 34 | 55 | Right labium major mass | 8 | MMS | NED |
Hammonds and Hendi [6] | 35 | 59 | Right labium major mass | 4 | MMS | NED |
Doufekas et al. [3] | 36 | 39 | Left labium major nodule | N/A | Incisional biopsy | MMS with primary closure. NED at 3 years |
Zizi-Sermpetzoglou et al. [27] | 37 | 66 | Mons pubis | N/A | WLE | NED |