Primitive neuroectodermal tumor (PNET) of the lung in an adult woman

Table 1 Differential diagnostic markers of small-blue- round-cell tumors in lung

IHC markers	CD99	CD56	Vim	TTF	Syn	Chr	CD34	LCA (CD45)	CD10	CD15	CK7	AE1/AE3	CK(HMW)	Calret	h-Cal	Desmin	SMA	HBME-1
Tumor types
PNET	++	+/-	+	-	+/-	-	-	-	-	-	-	+/-	-	-	-	-	-	-
Desmoplastic small round cell tumor of lung	-	-	++	-	-	-	-	-	-	-	-	++	-	-	-	-	-	-
Small cell carcinoma of the lung	-	+	-	++	+	+	-	-	-	-	-	++	-	+	-	-	-	-
Lung carcinoid	-	-	-	+	++	++	-	-	-	-	-	++	-	-	-	-	-	-
Metastasis of small cell carcinomas of other origin	-	+/-	-	+	-	-	-	-	-	-	+	+	+	-	-	-	-	-
Pulmonary rhabdomyosarcoma	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	+	-	-
NHL	+/-	-	-	-	-	-	-	++	+	+	-	-	-	-	-	-	-	-

Calret, calretinin; Chr, chromogranin; CK7, cytokeratin 7; CK(HMW), high molecular weight cytokeratin; HBME-1 – mesothelial cell marker; h-Cal, h-caldesmon; IHC, immunohistochemistry; LCA, leukocyte common antigen; NHL, non-Hodgkin’s lymphoma; PNET, primitive neoroectodermal tumor; SMA, smooth muscle actin; Syn, Synaphtophysin; TTF, thyroid transcription factor; Vim, vimentin.

ISSN: 1477-7819