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Table 3 Cox regression model for multivariate analyses of prognostic factor in MBs

From: DJ-1 is activated in medulloblastoma and is associated with cell proliferation and differentiation

Variable

Hazard ratio

95% confidence interval

P value

Age (≤3 years versus >3 years)

0.396

0.140 to 1.118

0.080

Gender (male versus female)

1.421

0.485 to 4.160

0.521

WHO histological subtype (classic versus desmoplastic)

0.931

0.308 to 2.808

0.899

Tumor location (fourth ventricle versus outside fourth ventricle)

1.201

0.404 to 3.573

0.741

Residual tumor size (≤1.5 cm2versus >1.5 cm2)

0.391

0.139 to 1.102

0.075

Metastatic status (M0versus M1)

1.720

0.310 to 9.546

0.534

Tumor risk (standard versus high)

0.695

0.041 to 11.92

0.802

Differentiation (differentiated versus undifferentiated)

0.348

0.121 to 0.998

0.050

MIB-1 index (low versus high)

5.949

1.986 to17.814

0.001

DJ-1 expression (low versus high)

4.531

1.443 to14.223

0.009

p-Akt expression (low versus high)

0.765

0.217 to 2.698

0.678