Table 5 Multivariate Cox proportional hazards model of 5-year overall survival
From: Does young age influence the prognosis of colorectal cancer: a population-based analysis
Event (n(%)) | Adjusted hazard ratio | 95% CI | P value | |
|---|---|---|---|---|
Diagnosis age group | <0.0001 | |||
45-79 | 661 (45.31) | 1.29 | 0.85-1.97 | |
80+ | 371 (66.61) | 1.95 | 1.27-3.01 | |
<45 | 23 (32.86) | 1 | Ref | |
Gender | 0.0045 | |||
Female | 478 (49.64) | 1 | Ref | |
Male | 577 (51.38) | 1.2 | 1.06-1.36 | |
Collaborative stage | <0.0001 | |||
I | 116 (28.78) | 1 | Ref | |
II | 194 (33.74) | 1.22 | 0.96-1.56 | |
III | 284 (46.56) | 1.72 | 1.34-2.20 | |
IV | 413 (94.08) | 6.12 | 4.73-7.91 | |
Unknown/NA | 48 (81.36) | 2.48 | 1.71-3.59 | |
Income quintile | 0.0003 | |||
1 | 276 (59.74) | 1 | Ref | |
2 | 244 (53.74) | 1.09 | 0.91-1.30 | |
3 | 209 (47.83) | 0.95 | 0.79-1.14 | |
4 | 165 (44.12) | 0.91 | 0.75-1.11 | |
5 | 139 (41.49) | 0.74 | 0.60-0.91 | |
NF | 22 (91.67) | 1.89 | 1.21-2.95 | |
Grade/differentiated | 0.0004 | |||
1 - well differentiated | 43 (34.68) | 1 | Ref | |
2 - moderately differentiated | 624 (45.32) | 1.15 | 0.84-1.58 | |
3 - poorly differentiated | 152 (57.79) | 1.59 | 1.13-2.25 | |
4 - undifferentiated | 5 (62.50) | 1.93 | 0.76-4.92 | |
9 - not determined/not available | 231 (73.57) | 1.52 | 1.08-2.14 | |
Comorbidity | <0.0001 | |||
CCI count <1 | 239 (28.55) | 1 | Ref | |
CCI count =1 | 454 (59.35) | 2.06 | 1.72-2.47 | |
CCI count >1 | 362 (74.79) | 2.9 | 2.41-3.49 | |
Surgery type | <0.0001 | |||
Major surgery | 707 (43.43) | 0.32 | 0.26-0.40 | |
Local resection | 15 (25.86) | 0.18 | 0.09-0.35 | |
Polypectomy | 27 (38.57) | 0.51 | 0.33-0.80 | |
None | 306 (92.73) | 1 | Ref | |
Chemotherapy type | <0.0001 | |||
None | 690 (51.49) | 1 | Ref | |
Neoadjuvant | 19 (35.85) | 0.76 | 0.48-1.22 | |
Adjuvant | 254 (43.94) | 0.6 | 0.50-0.72 | |
Palliative | 83 (90.22) | 0.4 | 0.30-0.52 | |
Adjuvant with local procedure | 9 (39.13) | 1.08 | 0.47-2.51 |