Clinical and pathological features of five-year survivors after pancreatectomy for pancreatic adenocarcinoma

Table 3 Univariate analysis of factors affecting five-year survival after pancreatectomy for pancreatic adenocarcinoma

Characteristics	Short-term survivors (n = 129)	Five-year survivors (n = 18)	P value
Gender
Male	72	13	0.21
Female	57	5
Age (years)
Median (range)	67 (33-85)	65 (46-76)	0.28
Tumor location
Head	85	12	1
Body/tail	44	6
Tumor size (cm)
Median (range)	3.5 (1.2-18)	3.2 (1.2-5.5)	0.52
≤2 cm	14	5	0.06
>2 cm	115	13
Histologic differentiation
Grade 1-2	102	11	0.13
Grade 3-4	27	7
T classification
T1-T2	14	3	0.44
T3-T4	115	15
N classification
N0	49	10	0.2
N1	80	8
Number of resected lymph nodes
Median (range)	25 (2100)	17 (258)	0.51
Number of lymph node metastasis
≤2	95	18	0.01
≥3	34	0
CA19-9 level (U/mL)
Median (range)	172 (223009)	30.5 (23221)	0.02
≤40	34	12	0
>40	94	6
Resection margin
R0	58	14	0.01
R1-R2	71	4
Adjuvant therapy
Yes	19	1	0.47
No	110	17
Serosal invasion
Present	81	10	0.61
Absent	48	8
Retroperitoneal invasion
Present	91	11	0.58
Absent	36	6
Intrapancreatic common bile duct invasion
Present	61	7	0.62
Absent	68	11
Lymphatic permeation
Present	113	16	1
Absent	16	2
Vascular permeation
Present	63	8	0.8
Absent	66	10
Intrapancreatic nerve invasion
Present	118	13	0.03
Absent	13	5
Portal vein resection
Present	31	2	0.37
Absent	98	16
Intraoperative radiation therapy
Present	11	3	0.38
Absent	118	15

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