Skip to main content

Table 3 Univariate analysis of factors affecting five-year survival after pancreatectomy for pancreatic adenocarcinoma

From: Clinical and pathological features of five-year survivors after pancreatectomy for pancreatic adenocarcinoma

Characteristics Short-term survivors (n = 129) Five-year survivors (n = 18) P value
Gender    
Male 72 13 0.21
Female 57 5  
Age (years)    
Median (range) 67 (33-85) 65 (46-76) 0.28
Tumor location    
Head 85 12 1
Body/tail 44 6  
Tumor size (cm)    
Median (range) 3.5 (1.2-18) 3.2 (1.2-5.5) 0.52
≤2 cm 14 5 0.06
>2 cm 115 13  
Histologic differentiation    
Grade 1-2 102 11 0.13
Grade 3-4 27 7  
T classification    
T1-T2 14 3 0.44
T3-T4 115 15  
N classification    
N0 49 10 0.2
N1 80 8  
Number of resected lymph nodes    
Median (range) 25 (2100) 17 (258) 0.51
Number of lymph node metastasis    
≤2 95 18 0.01
≥3 34 0  
CA19-9 level (U/mL)    
Median (range) 172 (223009) 30.5 (23221) 0.02
≤40 34 12 0
>40 94 6  
Resection margin    
R0 58 14 0.01
R1-R2 71 4  
Adjuvant therapy    
Yes 19 1 0.47
No 110 17  
Serosal invasion    
Present 81 10 0.61
Absent 48 8  
Retroperitoneal invasion    
Present 91 11 0.58
Absent 36 6  
Intrapancreatic common bile duct invasion    
Present 61 7 0.62
Absent 68 11  
Lymphatic permeation    
Present 113 16 1
Absent 16 2  
Vascular permeation    
Present 63 8 0.8
Absent 66 10  
Intrapancreatic nerve invasion    
Present 118 13 0.03
Absent 13 5  
Portal vein resection    
Present 31 2 0.37
Absent 98 16  
Intraoperative radiation therapy    
Present 11 3 0.38
Absent 118 15