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Table 1 Clinical and pathological data of the patient a

From: Gastroenteropancreatic neuroendocrine tumour arising in Meckel’s diverticulum coexisting with colon adenocarcinoma

  Colon adenocarcinoma Neuroendocrine tumour
Tumour size 3.5 × 3.0 × 2.6 cm 3 × 2 × 2 cm
Fat tissue invasion + -
Lymph node invasion + (10/23) - (0/23)
Perineural invasion + -
Vascular invasion + -
Lymphatic vessel invasion + +
Muscularis propria invasion + +
Serosal invasion + -
Resection margins - -
Tumour necrosis - -
CKAE1/AE3 + +
CgA + +
KRAS - Not applicable
Synaptophysin + +
Ki-67 60% 3%
Mitoses/10 hpf >20 ≤2
Grade of the cancer High grade (G3) Low grade (G1)
Astler-Coller classification[4] D Not applicable
TNM stage pT3pN2bpM1a pT3pN0pM0
AJCC clinical stage[5] IVA IIB
  1. aAJCC, American Joint Committee on Cancer; CgA, Chromogranin A; CKAE1/AE3, Cytokeratin AE1/AE3; hpf, High-power fields; Ki-67, Antigen Ki-67; KRAS, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; TNM, Tumour, node, metastasis classification of malignant tumours.