Table 1 Association between neogenin mRNA and protein levels and clinicopathological factors from breast cancer

Age (years)

≥65

4 (7.4)

0.042 ± 0.035

0.060

<65

50 (92.6)

0.270 ± 0.323

Tumor size (cm)

≤2.00

24 (44.4)

0.298 ± 0.373

0.959

2.01-5.00

26 (48.1)

0.217 ± 0.280

≥5.00

4 (7.4)

0.372 ± 0.412

Histology grade

I

1 (1.9)

0.132 ± 0

0.032

II

29 (53.7)

0.330 ± 0.343

III

24 (44.4)

0.192 ± 0.313

Stage

I

12 (22.2)

0.206 ± 0.319

0.818

II

19 (35.2)

0.292 ± 0.322

III

14 (25.9)

0.254 ± 0.357

IV

9 (16.7)

0.302 ± 0.368

Lymph node metastasis

Yes

35 (64.8)

0.320 ± 0.356

0.16

No

19 (35.2)

0.164 ± 0.257

Vascular invasion

Yes

38 (70.4)

0.272 ± 0.357

0.755

No

16 (29.6)

0.247 ± 0.268

Subtype

Luminal A

13 (24.1)

0.407 ± 0.400

0.484

Luminal B

14 (25.9)

0.217 ± 0.314

H type

14 (25.9)

0.199 ± 0.236

TNBC

13 (24.1)

0.244 ± 0.356

ER

+

27 (50)

0.309 ± 0.364

0.387

-

27 (50)

0.221 ± 0.295

PR

+

21 (38.9)

0.279 ± 0.318

0.908

-

33 (61.1)

0.256 ± 0.344

HER2

+

21 (38.9)

0.239 ± 0.290

0.918

-

33 (61.1)

0.281 ± 0.358

Ki67

+

39 (72.2)

0.256 ± 0.333

0.128

-

15 (27.8)

0.287 ± 0.335

p53

+

21 (38.9)

0.308 ± 0.371

0.292

-

33 (61.1)

0.237 ± 0.305