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Table 4 Results of the univariate and multivariate cox regression analysis of disease-free survival

From: Difference in prognostic values of maximal standardized uptake value on fluorodeoxyglucose-positron emission tomography and cyclooxygenase-2 expression between lung adenocarcinoma and squamous cell carcinoma

  Univariate Multivariate
  HR 95% CI P value HR 95% CI P value
A) Adenocarcinoma
Pathological stage 1.26 1.14-1.10 0.001 1.15 1.02-1.30 0.019
SUVmax 19.42 2.58-146.0 0.001 9.19 1.10-76.54 0.040
Cox-2 expression 4.08 1.18-14.04 0.026 1.57 0.40-6.22 0.521
Ki-67 expression 4.44 1.59-12.38 0.004 1.77 0.54-5.77 0.342
VEGF expression 5.52 1.27-23.94 0.023 1.67 0.36-7.78 0.515
B) Squamous cell carcinoma
Pathological stage 1.16 0.99-1.36 0.073 1.09 0.88-1.36 0.432
SUVmax 2.46 0.45-13.43 0.300 1.14 0.14-9.40 0.906
Cox-2 expression 9.46 1.10-81.40 0.041 7.36 1.04-72.05 0.048
Ki-67 expression 1.68 0.31-9.20 0.548 1.32 0.23-7.54 0.753
VEGF expression 0.52 0.10-2.84 0.450 0.62 0.89-4.31 0.627
  1. Pathological stage: I versus II + III. CI, confidence interval; Cox-2, cyclooxygenase-2; HR, hazard ratio; SUVmax, maximal standardized uptake value; VEGF, vascular endothelial growth factor.