Large cell neuroendocrine carcinoma of the ovary: a case report and a brief review of the literature

Table 1 Clinicopathologic review, adjuvant treatment, CA125 levels, and follow-up periods of reported cases

Author	Mean age (years)	Chief complaint	Adjuvant treatment	CA125 (u/ml)	Follow-up periods (months)
Lindboe et al. [2]	64	Abdominal discomfort, nausea	Cisplatin + Bleomycin + Etoposide	380	9
Shakuntala et al. [14]	40	Abdominal distension	Cisplatin + Etoposide	280	6
Hinde et al.[15]	54	Abdominal distension	Carboplatin + Paclitaxcel	_	8
Dundr et al. [8]	73	Dysarthria, difficulty in verbal expression because of brain metastasis	Carboplatin + Paclitaxcel	94	12
Dundr et al. [8]	73		Cyberknife on brain lesion
Tsuji et al. [17]	46	Abdominal distension	Carboplatin + Paclitaxcel	914	Died after 4 months postoperatively
Aslam et al. [13]	76	Abdominal pain	None	Within the normal range	Died postoperatively
Chenevert et al. [16]	53	Abdominal mass	Carboplatin + Paclitaxcel	80	Died after 3 months postoperatively
Chenevert et al. [16]	53	Abdominal distension	Cisplatin + Etoposide	5.7	Died after 7 months postoperatively
Behnam et al. [5]	27	Pelvic mass	Carboplatin + Paclitaxcel		10
Veras et al.[3] 11 cases	22 to 63 [46.7]	6: abdominal pain			Mean survival: 12
		6: abdominal pain			Mean follow-up periods: 28
		3: abdominal bloating
		1: pelvic mass
		1: postmenopausal bleeding
Ki et al.	77
Ki et al.		Abdominal distension	Carboplatin + Etoposide	124	Died after 1.5 months postoperatively
	58	Abdominal discomfort	Cisplatin + Paclitaxcel	none	Died after 17 months postoperatively
			Single Docetaxel
	67	Urinary frequency	Carboplatin + Paclitaxcel	71.8	5

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