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Table 3 Disease-free survival analysis by the Cox proportional hazards regression model in 146 cases of IDC-NOS

From: Prognostic value of poorly differentiated clusters in invasive breast cancer

    Variable

Univariate

Multivariate

Hazard ratio

95% confidence interval

P

Hazard ratio

95% confidence interval

P

Age 40 or younger/>40

0.501

0.257 to 0.975

0.042*

0.826

0.414 to 1.648

0.587

T stage: T1/T2/T3

2.554

1.451 to 4.497

0.001*

3.135

1.672 to 5.879

<0.001*

N stage: N0/N1/N2 or 3

2.795

1.921 to 4.064

<0.001*

2.922

1.266 to 6.744

0.012*

Grade: G1/G2/G3

1.455

0.829 to 2.554

0.191

  

Not assessed

Lymphovascular invasion: negative/positive

3.809

2.095 to 6.925

<0.001*

0.593

0.183 to 2.155

0.427

Estrogen receptor or progesterone receptor: negative/positive

1.009

0.555 to 1.834

0.978

  

Not assessed

HER-2: negative/positive

2.064

1.031 to 4.133

0.041

0.820

0.383 to 1.758

0.610

Triple negative status: no/yes

1.365

0.731 to 2.551

0.329

  

Not assessed

Poorly differentiated cluster grade: G1/ G2/ G3

5.086

2.998 to 8.628

<0.001*

3.811

1.992 to 7.289

<0.001*

Tumor budding: G1/G2/G3

2.554

1.721 to 3.792

<0.001*

1.808

1.159 to 2.820

0.009*

  1. *P <0.05.