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Table 1 Patient baseline characteristics (n = 1,032)

From: HER-2 positive breast cancer is associated with an increased risk of positive cavity margins after initial lumpectomy

Characteristics

n

%

Age (y)

  

≤35

110

10.7

36–50

527

51.1

>50

395

38.3

cT stage

  

T1

575

55.7

T2

398

38.5

Tx

59

5.7

pT stage

  

T1

658

63.8

T2

271

26.2

Tx

103

10.0

pN stage

  

N0

736

71.3

N1

209

20.3

N2

50

4.8

N3

30

3.9

Unknown

7

0.7

Grade

  

G1

83

8.1

G2

590

57.4

G3

354

34.5

Menopausal status

  

Pre-

652

63.2

Post-

379

36.8

Margin status

  

Negative

823

79.7

Carcinoma in situ

87

8.4

Invasive carcinoma

122

11.8

Presence of LVI

114

11.9

Presence of EIC

102

9.9

ER or PR positive

826

80.0

HER-2 positive

216

12.0

Histological subtype

  

Invasive ductal carcinoma

805

78.0

Presence of DCIS component

83

8.0

Invasive lobular carcinoma

29

2.8

Other

115

11.2

Breast cancer subtype

  

Luminal A

540

52.3

Luminal B

154

14.9

Luminal-HER-2

132

12.8

HER-2 positive

84

8.1

TN

122

11.8

  1. EIC, Extensive intraductal component; LVI, Lymphovascular invasion; ER, Estrogen receptor; PR, Progesterone receptor; HER-2, Human epidermal growth factor receptor 2; DCIS, Ductal carcinoma in situ; IDC, Invasive ductal carcinoma; TN, Triple-negative.