Skip to main content

Table 3 Univariate analysis of factors associated with OS and DFS

From: High expression of periostin is dramatically associated with metastatic potential and poor prognosis of patients with osteosarcoma

Variable

OS

DFS

Mean survival month

95% CI

P value

Mean survival month

95% CI

P value

Periostin

      

Negative

51

42.191-60.975

0.003

42

32.503-50.663

0.001

Positive

31

26.533-35.347

23

19.578-29.222

Sex

      

Male

34

30.480-39.391

0.073

26

22.971-30.868

0.066

Female

31

25.388-36.612

23

16.055-29.945

Age at diagnosis (years)

      

<30

35

30.480-39.391

0.169

26

22.971-30.868

0.169

>30

31

25.388-36.612

23

16.055-29.945

Site of primary disease

      

Tibia

31

25.388-36.612

0.172

26

22.971-30.868

0.176

Femur

31

25.042-38.833

25

18.766-31.234

Humerus

35

19.171-53.424

28

12.358-42.842

Other

41

36.846-45.617

32

28.577-35.500

Histologic subtype (n)

      

Special

67

60.383-74.817

0.000

56

46.412-65.988

0.000

Conventional

32

28.044-36.096

24

20.849-27.852

Enneking stage

      

I, II

40

35.700-44.668

0.000

31

27.668-35.556

0.000

III

15

10.727-19.580

9

5.144-13.318

Size (at diagnosis) (cm)

      

< 5

44

39.965-49.193

0.000

35

31.469-39.636

0.000

> 5

19

15.395-23.938

13

9.586-16.914

Alkaline phosphatase (u/L)

      

< 500

33

30.480-38.391

0.162

26

22.971-30.868

0.151

> 500

31

25.388-36.612

23

16.055-29.945

Serum albumin (g/L)

      

< 30

35

31.224-39.031

0.211

27

22.845-31.547

0.278

> 30

31

25.308-35.578

24

18.454-28.567

ESR (mm/hr)

      

< 30

34

31.135-39.023

0.060

26

21.975-30.086

0.126

> 30

31

25.886-34.479

23

19.333-28.792

  1. CI: Confidence interval; DFS: disease free survival; ESR: erythrocyte sedimentation rate; OS: Overall survival;
  2. P <0.05 was considered to be statistically significant.