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Table 2 Periostin expression status in relation to selected clinicopathologic features in 62 osteosarcoma patients (cases)

From: High expression of periostin is dramatically associated with metastatic potential and poor prognosis of patients with osteosarcoma

Clinicopathologic data

Case number

Periostin

χ 2

P value

OR

95% CI

Positive

Negative

Sex

       

Male

33

26

7

0.156

0.693

0.774

0.216 ~ 2.768

Female

29

24

5

Age at diagnosis (years)

       

<30

42

34

8

0.008

0.929

0.941

0.247 ~ 3.592

>30

20

16

4

Site of primary disease

       

Tibia

26

22

4

0.995

0.802

  

Femur

16

13

3

Humerus

10

7

3

Other

10

8

2

Histologic subtype

       

Special

5

0

5

22.661

0.000

8.143

4.069 ~ 16.297

conventional

57

50

7

Enneking stage

       

I, II

49

37

12

3.948

0.047

1.324

1.129 ~ 1.553

III

13

13

0

Size (at diagnosis) (cm)

       

<5

38

27

11

5.787

0.016

9.370

1.123 ~ 78.169

>5

24

23

1

Alkaline phosphatase (u/L)

       

<500

35

28

7

0.021

0.884

0.909

0.254 ~ 3.258

>500

27

22

5

Serum albumin (g/L)

       

<30

22

18

4

0.03

0.862

0.889

0.235 ~ 3.367

>30

40

32

8

ESR (mm/hr)

       

<30

45

36

9

0.044

0.834

0.857

0.202 ~ 3.636

>30

17

14

3

  1. CI: Confidence interval; ESR: erythrocyte sedimentation rate; OR: the odds ratio; PN: Periostin.
  2. P <0.05 was considered to be statistically significant.