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Table 1 Clinical data of 244 patients with follicular and Hürthle cell neoplasms with diameter 2 cm or less

From: Preoperative serum thyroglobulin concentration as a predictive factor of malignancy in small follicular and Hürthle cell neoplasms of the thyroid gland

Characteristic Subgroup Benign N = 182 (%) Carcinoma N = 62 (%) Chi-square test P value
Age (years) 45 or younger 57 (24%) 23 (9%) 0.44
  Older than 45 125 (51%) 39 (16%)  
  65 or younger 163 (67%) 54 (22%) 0.64
  Older than 65 19 (8%) 8 (3%)  
Sex Male 17 (7%) 13 (5%) 0.024
Female 165 (68%) 49 (20%)
Dominant tumor In multinodular goiter 61 (25%) 23 (9%) 0.64
Solitary 121 (50%) 39 (16%)
Tumor diameter (cm) 1 or less 42 (17%) 13 (5%) 0.86
  More than 1 140 (58%) 49 (20%)  
Thyroid volume (ml) 29 or less 149 (61%) 47 (19%) 0.36
  30 or more 33 (14%) 15 (6%)  
  49 or less 169 (70%) 52 (21%) 0.045
  50 or more 13 (5%) 10 (4%)  
Serum Tg concentration (ng/ml) 79 or less 120 (49%) 28 (11%) 0.004
  80 or more 62 (26%) 34 (14%)  
  299 or less 168 (69%) 51 (21%) 0.031
  300 or more 14 (6%) 11 (4%)