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Table 1 Clinical data of 244 patients with follicular and Hürthle cell neoplasms with diameter 2 cm or less

From: Preoperative serum thyroglobulin concentration as a predictive factor of malignancy in small follicular and Hürthle cell neoplasms of the thyroid gland

Characteristic

Subgroup

Benign N = 182 (%)

Carcinoma N = 62 (%)

Chi-square test P value

Age (years)

45 or younger

57 (24%)

23 (9%)

0.44

 

Older than 45

125 (51%)

39 (16%)

 
 

65 or younger

163 (67%)

54 (22%)

0.64

 

Older than 65

19 (8%)

8 (3%)

 

Sex

Male

17 (7%)

13 (5%)

0.024

Female

165 (68%)

49 (20%)

Dominant tumor

In multinodular goiter

61 (25%)

23 (9%)

0.64

Solitary

121 (50%)

39 (16%)

Tumor diameter (cm)

1 or less

42 (17%)

13 (5%)

0.86

 

More than 1

140 (58%)

49 (20%)

 

Thyroid volume (ml)

29 or less

149 (61%)

47 (19%)

0.36

 

30 or more

33 (14%)

15 (6%)

 
 

49 or less

169 (70%)

52 (21%)

0.045

 

50 or more

13 (5%)

10 (4%)

 

Serum Tg concentration (ng/ml)

79 or less

120 (49%)

28 (11%)

0.004

 

80 or more

62 (26%)

34 (14%)

 
 

299 or less

168 (69%)

51 (21%)

0.031

 

300 or more

14 (6%)

11 (4%)