Table 2 Multivariate analysis of GLI1 mRNA expression and other clinicopathological variables for patient survival

GLI1 mRNA expression

Low

1

0.0030

High

3.1

1.5-6.2

Age (years)

≤65

1

0.23

>65

1.3

0.83-2.2

Gender

Male

1

0.86

Female

0.92

0.37-2.2

Cigarette smoking

Never smoked

1

0.69

Smoker (ex or current)

1.2

0.48-3.1

Tumor differentiation

Well

1

Moderately

1.7

0.83-3.6

0.16

Poorly

2.5

1.1-5.8

0.030

Tumor stage

II

1

III

2.5

1.5-4.5

<0.001

IV

4.2

1.7-9.8

0.0027

EGFR gene mutation status

Wild-type

1

Mutation (+)

1.1

0.58-2.0

0.77

Pre/postoperative chemo- and/or radiotherapy

No

1

Yes

0.67

0.33-1.4

0.29