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Table 2 Treatment modalities and therapeutic results of reported CASTLEs[5, 6, 1013]

From: Extrathyroid carcinoma showing thymus-like differentiation (CASTLE): a new case report and review of the therapeutic role of neck dissection and radiotherapy

Treatment modality

 

Recurrence

 

NED

Excision only

 

6

 

7

Excision + RT

 

2

 

4

Excision + RT*

 

0

 

1

Excision + ND

N (+)

1

N (+)

0

 

N (-)

0

N (-)

3

Excision + ND*

N (-)

0

N (-)

1

Excision + ND + RT

N (+)

4

N (+)

2

 

N (-)

0

N (-)

2

Excision + ND + RT*

N (+)

0

N (+)

1

Total

 

13

 

21

  1. *The three cases of extra-thyroid CASTLE.
  2. N (+), node positive in neck dissection specimen; N (-), node negative in neck dissection specimen; ND, neck dissection; NED, no evidence of disease; RT, radiation therapy.