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Table 3 Immunohistochemical marker expression in respective NPI groups

From: Classification of patients with breast cancer according to Nottingham Prognostic Index highlights significant differences in immunohistochemical marker expression

Marker

NPI 1

NPI 2

NPI 3

P value [Kruskal-Wallis]

Neg.

Pos.

Neg.

Pos.

Neg.

Pos.

ER

1

39

7

33

18

22

P < 0.01

2.50%

97.50%

17.50%

82.50%

45.00%

55.00%

PR

3

37

10

30

25

15

P < 0.01

7.50%

92.50%

25%

75%

62.50%

37.50%

HER-2

37

3

32

8

26

14

P = 0.01

92.50%

7.50%

80%

20%

65%

35%

Ki-67 low

3

37

12

28

31

9

P < 0.01

7.50%

92.50%

30%

70%

77.50%

22.50%

Ki-67 high

37

3

28

12

9

31

P < 0.01

92.50%

7.50%

70%

30%

22.50%

77.50%

Bcl-2

1

39

9

31

19

21

P < 0.01

2.50%

97.50%

22.50%

77.50%

47.50%

52.50%

p53

21

19

19

21

11

29

P = 0.57

52.50%

47.50%

47.50%

52.50%

27.50%

72.50%