Figure 3
From: Breast carcinoma with choriocarcinomatous features: a case report and review of the literature
Histology of breast carcinoma with choriocarcinomatous features (BCCF) metastatic to the kidney. (A) Hematoxylin-eosin (HE) staining at a low magnification. The BCCF metastatic to the kidney (presented as a thin border of intact choriocarcinoma, indicated with black lines) is well-circumscribed and cystic, surrounded by normal renal tissue, with extensive hemorrhage around it. Error bars represent 100 μm. (B) HE staining at a high magnification. In the background of hemorrhage, giant cells with prominent pleomorphic nuclei, and abundant acidophilic and vacuolated cytoplasm resembling cytotrophoblastic cells could be seen. Error bars represent 50 μm. (C) Immunohistochemistry of human chorionic gonadotropin (HCG) demonstrates that all the cancer cells show strong HCG staining. Error bars represent 50 μm.