Table 5 Significant prognostic factors evaluated by Cox proportional hazards analysis

Tumor location

Lower third

0.54 (0.26-1.11)

0.095

Middle third

0.53 (0.25-1.09)

0.08

Upper third

0.91 (0.43-1.9)

0.8

Whole stomach

1

Tumor stage

I

0.15 (0.08-0.28)

<0.001

II

0.35 (0.2-0.62)

<0.001

III

0.69 (0.41-1.15)

0.16

IV

1

Treatment period

1980-1989

1.25 (0.95-1.65)

0.1

1990-1999

1.02 (0.76-1.36)

0.86

2000-2010

1

Lauren classification

Diffuse

1.34 (0.86-1.73)

0.78

Indeterminate

1.52 (1.2-1.81)

0.41

Intestinal

1

Lymph nodes retrieved

<15

2.41 (1.07-2.86)

15-30

1.34 (1.02-2.15)

0.009

≥30

1

Patients with complications

Yes

1.19 (0.93-1.5)

0.156

No

1

Multivisceral resections

Yes

1.07 (0.81-1.43)

0.609

No

1

Margin status

R1/R2

1.97 (1.2-3.1)

0.003

R0

1