Table 4 Factors affecting five-year overall survival according to univariate analysis

Gender

Male

581 (62)

39.6

46.6

51.3

<0.001

Female

355 (38)

37.8

52.2

53.4

0.02

Age

<65

503 (53.7)

45.8

53

55

0.001

≥65

433 (46.3)

31.1

42

47

0.004

Tumor location

Lower third

405 (43.3)

40.2

50.5

54.5

0.003

Middle third

337 (36)

46.2

59.5

57.9

0.03

Upper third

179 (19.1)

27

30.6

38.1

0.03

Whole stomach

15 (1.6)

18

25.3

33.4

0.027

Lauren classification

Diffuse

402 (42.9)

32.8

47.5

47

0.003

Intestinal

449 (48)

48.8

48.1

59.1

0.017

Indeterminate

85 (9.1)

37

34.3

35

0.18

Tumor stage

I

255 (27.2)

77

74.9

76.8

0.035

II

197 (21.1)

51.2

61.6

67.1

0.075

III

319 (34.1)

28.5

31.4

38.7

0.024

IV

165 (17.6)

11.9

10.6

14.6

0.320

Type of gastrectomy

Total gastrectomy

450 (48)

43.9

46.5

50.8

0.12

Distal subtotal gastrectomy

433 (46.2)

45.9

51.6

57.6

<0.001

Margin status

R0

723 (77.2)

51

60.5

64.5

<0.001

R1/2

213 (22.8)

20

23

26

0.158

Adjuvant therapy

Yes

361 (39)

27.2

29.6

35.2

0.138

No

571 (61)

56.1

57

55.3

0.286

Multivisceral resections

195 (21)

24.9

31.7

49.6

<0.001

Lymph nodes retrieved

<15

225 (24)

22.4

30.4

39.2

<0.001

15-30

327 (35)

48.6

43.7

50.7

0.279

≥30

384 (41)

59

58.8

64

0.03