From: Sublobar resection versus lobectomy in solid-type, clinical stage IA, non-small cell lung cancer
Variables | Lobectomy (N = 133) | Sublobar resection (N = 31) | P value |
---|---|---|---|
Mean ± SD or n (%) | Mean ± SD or n (%) | ||
Histology | 0.012 | ||
Adenocarcinoma | 109 (82.0) | 18 (58.1) | |
Squamous | 16 (12.0) | 10 (32.36) | |
Others | 8 (6.0) | 3 (9.7) | |
Differentiation | 0.116 | ||
Well | 51 (38.4) | 6 (19.4) | |
Moderate | 65 (48.9) | 21 (67.7) | |
Poor | 17 (12.8) | 4 (12.9) | |
Tumor size | 2.19 ± 0.75 | 1.99 ± 0.75 | 0.239 |
p T stage | 0.694 | ||
pT1a | 67 (50.4) | 17 (54.8) | |
Margin | 3.51 ± 2 | 0.95 ± 1.16 | <0.001 |
Positive margin | 1 (0.8) | 7 (22.6) | <0.001 |
Visceral pleural invasion | 15 (11.3) | 3 (6.7) | 1.000 |
Lymphatic vessel invasion | 29 (21.8) | 4 (12.9) | 0.450 |
Blood vessel invasion | 3 (2.3) | 0 (0) | 1.000 |
Number of LN harvest | 10.50 ± 7.6 | 1.74 ± 5.09 | <0.001 |
LN metastasis | 20 (15.0) | 0 (0) | 0.015 |
Number of positive LNs | 0.53 ± 1.90 | 0 (0) | 0.019 |
N2 positive | 10 (7.5) | 0 (0) | 0.211 |
p Stage | 0.156 | ||
p Stage I | 112 (84.2) | 30 (96.8) | |
p Stage II | 11 (8.3) | 0 (0) | |
p Stage III | 10 (7.5) | 1 (3.2) | |
Recurrence | 35 (26.3) | 19 (61.3) | <0.001 |
Lung to lung metastasis | 8 (6) | 6 (19.4) | |
Margin | 4 (3) | 4 (12.9) | |
Mediastinal lymph node | 6 (4.5) | 5 (16.1) | |
Distant metastasis | 17 (12.8) | 4 (12.9) |