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Table 4 Pooled outcomes of subgroup analysis for studies with comparable tumor size or risk index

From: Laparoscopic versus open resection for gastric gastrointestinal stromal tumors: an updated systematic review and meta-analysis

Outcomes Number of studies Sample size Heterogeneity (P, I2) Overall effect size 95% CI of overall effect P
   LAP OPEN     
Operation time (min) 13 371 377 <0.001, 81% WMD = -1.06 -16.93, 14.81 0.90
Blood loss (ml) 11 300 302 <0.001, 71% WMD = -58.20 -81.76, -34.65 <0.01
Time to first flatus (d) 6 129 142 0.09, 47% WMD = -1.28 -1.60, -0.97 <0.01
Time to oral intake (d) 7 212 241 0.02, 61% WMD = -1.77 -2.18, -1.35 <0.01
Hospital stay (d) 11 309 339 0.006, 60% WMD = -2.87 -3.54, -2.21 <0.01
Overall complications 12 341 345 0.74, 0% RR = 0.49 0.30, 0.81 <0.01
Tumor size (cm) 13 371 377 0.23, 21% WMD = -0.57 -0.86, -0.29 <0.01
Recurrence 8 248 232 0.81, 0% RR = 0.66 0.31, 1.42 0.29
  1. CI, confidence interval; LAP, laparoscopic surgery; OPEN, open surgery; RR, risk ratio; WMD, weighted mean difference.