Table 5 Univariate analysis of permanent hypoparathyroidism
Permanent hypoparathyroidism | P-value | ||
|---|---|---|---|
Factors | No n = 434 | Yes n = 20 | |
Age | 50.5 ± 12.5 | 46.3 ± 12.2 | 0.059 |
Gender | 0.587 | ||
Male | 95 (21.9%) | 3 (15.0%) | |
Female | 339(78.1%) | 17 (85.0%) | |
Tumor size (mm) | 11.7 ± 9.1 | 12.9 ± 8.9 | 0.367 |
Tumor location | 0.180 | ||
Right | 166 (38.2%) | 5 (25.0%) | |
Left | 161 (37.1%) | 6 (30.0%) | |
Bilateral | 92 (21.2%) | 8 (40.0%) | |
Confined to isthmus | 15 (3.5%) | 1 (5.0%) | |
Tumor multiplicity | 127/434 (29.3%) | 6/20 (30.0%) | 0.559 |
Tumor bilaterality | 96/434 (22.1%) | 7/20 (35.0%) | 0.179 |
Preserved PTG number | 0.147 | ||
4 | 351 (80.9%) | 13 (65.0%) | |
3 | 74 (17.1%) | 6 (30.0%) | |
2 | 6 (1.4%) | 1 (5.0%) | |
1 | 3 (0.7%) | 0 | |
Incidental parathyroidectomy | 83/434 (19.1%) | 7/20 (35.0%) | 0.090 |
T classification | 0.285 | ||
T1 | 234(53.9%) | 7(35.0%) | |
T2 | 26(6.0%) | 2(10.0%) | |
T3 | 170(39.2%) | 11(55.0%) | |
T4 | 4(0.9%) | 0 | |
N classification | 0.008 | ||
N0 | 269(62.0%) | 6(30.0%) | |
N1 | 165(38.0%) | 14(70.0%) | |
TNM staging | 0.871 | ||
I | 258 (59.4%) | 11(55.0%) | |
II | 10 (2.3%) | 0 | |
III | 117 (27.0%) | 7(35.0%) | |
IV | 49 (11.3%) | 2(10.0%) | |
Extrathyroidal extension (minimal) | 197/434(45.4%) | 12/20(60.0%) | 0.253 |
CND | 0.663 | ||
None | 118 (27.2%) | 4 (20.0%) | |
Unilateral | 100 (23.0%) | 6 (30.0%) | |
Bilateral | 216 (49.8%) | 10 (50.0%) | |
Lateral ND | 65/434 (15.0%) | 6/20 (30.0%) | 0.106 |
Lateral LN metastasis | 0.683 | ||
None | 379 (87.3%) | 17 (85.0%) | |
Unilateral | 43 (9.9%) | 3 (15.0%) | |
Bilateral | 12 (2.8%) | 0 | |
Operation time (minutes) | 186.1 ± 80.0 | 183.5 ± 74.5 | 0.841 |
Retrieved central LN (no) | 5.5 ± 5.4 | 6.2 ± 6.6 | 0.743 |
Metastatic central LN (no) | 1.4 ± 2.8 | 1.5 ± 2.4 | 0.355 |
Drain amount (mL) | 224.7 ± 692.8 | 151.8 ± 152.4 | 0.188 |
Vocal cord paralysis | 1.000 | ||
None | 416(95.9%) | 20(100%) | |
Temporary | 17(3.9%) | 0 | |
Permanent | 1(0.2%) | 0 | |
Hematoma | 19/434(4.4%) | 0 | 1.000 |