Table 1 Clinical features of the patients with pancreatic metastases from primary breast cancer
Author and reference | Patients with pancreatic metastases (n) | Patients with primary breast cancer (n) and subtype | Age (years) | Disease--free interval (months) | Presenting symptoms | Localization of metastases at diagnosis | Characteristics of metastasis at diagnosis | Clinical management | Outcome (overall survival in months) |
|---|---|---|---|---|---|---|---|---|---|
Akashi [15] | 15 | 1 (lobular) | 47 | 41 | NR | Head of pancreas | Solitary | Pancreaticoduodenectomy | 28 |
Bonapasta [16] | 1 | 1 (ductal) | 51 | 24 | Jaundice, pain | Head of pancreas | Solitary | Cephalic pancreaticoduodenectomy | 36 |
Azzarelli [17] | 1 | 1 (lobular) | 49 | 43 | Jaundice | Head of pancreas | Solitary | Pancreaticoduodenectomy, RT | 72 |
Bednar [18] | 2 | 1 (lobular) | 75 | 96 | Jaundice, pain | Head of pancreas | Solitary | Pancreaticoduodenectomy | 48 |
1 (phyllodes) | 57 | 48 | Abdominal pain | Head of pancreas, lung | Widespread disease | CHT | 15 | ||
Crippa [19] | 13 | 1 (lobular) | 46 | 60 | Jaundice | Head of pancreas | Solitary | Pylorus preserving pancreaticoduodenectomy | 22 |
1 (lobular) | 70 | 36 | Jaundice, pain | Head of pancreas | Solitary | Pylorus preserving pancreaticoduodenectomy | 38 | ||
1 (lobular) | 57 | 84 | Jaundice, pain | Head of pancreas | Solitary | Pylorus preserving pancreaticoduodenectomy | 26 | ||
Dar [20] | 5 | 1(ductal) | 76 | 108 | NR | Pancreas, liver | Widespread disease | Palliative bypass | 6 |
Engel [21] | 1 | 1 (signet-ring cells) | 59 | 46 | Pruritis, dark urine | Head of pancreas | Solitary | By-pass, CHT | 15 |
Kitamura [22] | 1 | 1 (ductal) | 55 | 117 | Jaundice | Head of pancreas | Solitary | Percutaneous transhepaticcholangio-drainage | 1 |
Le Borgne [23] | 12 | 1 (lobular) | 48 | Synchronous | Jaundice | Head of pancreas | Solitary | Pancreaticoduodenectomy, CHT | 12 |
Mehta [24] | 1 | 1 (comedo type) | 30 | 36 | Jaundice, pruritis | Head of pancreas | Solitary | Pancreaticoduodenectomy, CHT, HT | 27 |
Mountney [25] | 1 | 1 (lobular) | 57 | 16 | Jaundice | Head of pancreas | Solitary | By-pass, HT | 24 |
Moussa [26] | 22 | 1 (ductal) | 53 | 132 | Acute pancreatitis | Head of pancreas | Solitary | RT, CHT, HT | 50 |
1 (lobular) | 35 | 45 | Abdominal mass | Body of pancreas | Solitary | Total pancreatectomy, CHT | 7 | ||
Nomizu [27] | 1 | 1 (lobular) | 46 | 80 | Jaundice | Head of pancreas | Solitary | Pancreaticoduodenectomy, CHT, HT | 18 |
Pan [28] | 6 | 1 (lobular) | 59 | 182 | Jaundice | Head of pancreas | Solitary | CHT, HT | 21 |
Pappo [29] | 1 | 1 (lobular) | 52 | 24 | Jaundice | Pancreas, gallbladder | Widespread disease | Bypass, HT | 16 |
Pérez Ochoa [30] | 2 | 1 (lobular) | 60 | 1 | Jaundice | Head of pancreas, | Widespread disease | Biliary stent, cephalic | 2 |
| Â | Â | Â | Â | Bone | Â | Pancreaticoduodenectomy, CHT | Â | ||
1 (ductal) | 55 | 108 | None | Tail of pancreas | Solitary | Distal pancreatectomy, splenectomy, CHT | 2 | ||
Tohnosu [31] | 1 | 1 (scirrhous type) | 54 | 52 | None | Tail of pancreas | Solitary | Distal pancreatectomy, CHT, HT | 5 |
Z’graggen [32] | 10 | 1 (lobular) | NR | 96 | Jaundice | Head of pancreas | Solitary | Biliary and gastric bypass (hepaticojejunostomy and gastrojejunostomy), CHT | 54 |