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Table 6 Sequential metastases after lung and liver metastases

From: Rectal cancer level significantly affects rates and patterns of distant metastases among rectal cancer patients post curative-intent surgery without neoadjuvant therapy

  Local first Lung first Liver first  
  Number of patients (%) Number of patients (%) Number of patients (%) P
  Solitary 45   Solitary 53   Solitary 42   
  Multiple 68 (100) Multiple 52 (100) Multiple 56 (100)  
Multiple Organs Lung 32 (47.0) Local 6 (11.5) Local 6 (10.7)  
Liver 23 (33.9) Liver 8 (15.4) Lung 44 (78.6)  
Bone 10 (14.7) Bone 28 (53.8) Bone 6 (10.7) 0.001
Brain 2 (2.9) Brain 12 (22.6) Brain 2 (3.6) 0.010
Carcinomatosis 7 (10.3) Carcinomatosis 6 (11.5) Carcinomatosis 3 (5.4) 0.185
  Systemic LN 22 (32.3) Systemic LN 16 (30.7) Systemic LN 18 (32.1) 0.120