Skip to main content

Table 5 Correlation of the risk of local recurrence and patterns of distant metastases with the location of the adenocarcinoma along the rectum

From: Rectal cancer level significantly affects rates and patterns of distant metastases among rectal cancer patients post curative-intent surgery without neoadjuvant therapy

Adenocarcinoma location 10.1-15 cm (n = 436) 5.1-10 cm (n = 331) 0-5 cm (n = 117)
  Patient no. (%) HR 95% CI Patient no. (%) HR 95% CI P Patient no. (%) HR 95% CI P
Recurrence in patients/Recurrence patterns               
  Local 36 (8.26) 1 - 50 (15.11) 1.885 1.23-2.89 0.004 23 (19.66) 2.786 1.65-4.70 <0.001
  Lung 57 (13.07) 1 - 73 (22.05) 1.760 1.25-2.49 0.001 38 (32.48) 3.187 2.11-4.81 <0.001
  Liver 58 (13.3) 1 - 45 (13.06) 1.012 0.69-1.49 0.951 12 (10.26) 0.832 0.45-1.55 0.563
  Bone 15 (3.44) 1 - 23 (6.95) 2.090 1.09-4.01 0.026 13 (11.11) 4.043 1.92-8.51 <0.001
  Brain 6 (1.38) 1 - 8 (2.42) 1.819 0.63-5.24 0.268 4 (3.42) 3.136 0.88-11.13 0.077
  Carcinomatosis 8 (1.83) 1 - 9 (2.72) 1.494 0.58-3.87 0.409 5 (4.27) 2.649 0.87-8.10 0.088
  Systemic LN 15 (3.44) 1 - 31 (9.37) 2.788 1.51-5.17 0.001 17 (14.53) 5.046 2.52-10.11 <0.001